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About our Herbathione Herbal Tincture and the Herbs we Use in our Spectrum Support Formulas |
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by Michael Lang |
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Glutathione is one of the body's most powerful natural antioxidants and is a sulfur- rich tripeptide bonded from the three amino acids Cysteine, Glutamine, and Glycine. One of it's most crucial functions is as Glutathione Peroxidase, which protects our body's cellular membranes from damage due to lipid peroxidation from hydrogen peroxide and other free radical challenges. Glutathione detoxifies many chemicals, including phenols, bacterial toxins, household chemicals, pesticides, and heavy metals.1 |
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Exposure to environmental toxins and genetically-acquired defects in sulfur metabolism, or "envirogenetic" compromises in glutathione synthesis may hinder our body's ability to detoxify the toxins we encounter in our environments.2 The absorption of orally administered glutathione can be limited and even IV administration can have limited duration of elevated plasma levels.3 Vitamin C, Alpha Lipoic Acid, along with other antioxidant vitamins and minerals facilitate enhanced synthesis and recycling of glutathione which may serve to raise its plasma levels.4,5,6,7 |
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HerbaThione, our herbal tincture, was carefully formulated to provide botanical antioxidant support of glutathione synthesis and recycling, as well as antioxidant, detoxification, immune, gastro-intestinal, & neurological function support. BrainChild Nutritionals is pleased to introduce this organically grown alcohol-free proprietary herbal extract blend to its line of quality liquid nutritional supplements. HerbaThione is an herbal tincture that combines the best of Western, Chinese, and Ayurvedic herbal traditions utilizing the following herbal antioxidant and liver protective constituents: |
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Ashwaganda Root |
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(Withania somnifera) |
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Known as "Ayurvedic Ginseng", Ashwaganda has been used for centuries as a nervous system rejuvenator/protectant, for immune support, and for support of sleep disturbances, wasting diseases, failure to thrive in children, joint and nerve pains. It supports detoxification via its antioxidant function in the recycling of glutathione and support of superoxide dismutase.8,9,10,11 |
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Burdock Root |
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(Arcticum lappa) |
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A mucilaginous herb that reduces inflammation and controls bacterial infection. Mild laxative. Supports lung, kidney, spleen, pituitary, lymphatic, thymus, and immune health. Blood cleanser and purifier, used with inflammatory conditions of chronic toxicity and for skin conditions. Promotes bile flow, liver cleansing, and enhanced liver glutathione. 12,13 |
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Chinese Astragalus Root |
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(Astragalus membranaceus) |
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A nourishing tonic that stimulates the immune system, spleen, lungs, adrenals, liver, circulatory, lymphatic, and urinary systems, lowers blood pressure and blood sugar levels. Aids digestion, promotes healing, inhibits lipid peroxidation. 14,15,16 |
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Fennel Seed |
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(Agastache foeniculum) |
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A sweet aromatic flavoring herb that also promotes gastrointestinal motility, the functions of the liver, kidneys, spleen and supports respiratory function. Relieves abdominal pain, colon disorders, gas, and gastrointestinal tract spasms. Also, a natural sulfur source. 17,18,19 |
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Ginkgo Biloba Leaf |
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(Gingko Biloba) |
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Powerful antioxidant, dilates bronchial tubes and blood vessels, specifically increases cerebral and cardiac blood flow and available cerebral oxygen, controls allergic responses, and improves cardio-pulmonary function. Has anti-fungal and antibacterial effects. Helpful for depression, Used for asthma, allergic inflammatory responses, cerebral insufficiency. Inhibits allergic response. Improves digestion. Increases cellular glutathione and liver-specific glutathione S-transferase.20,21. |
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Gotu Kola Leaf |
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(Centella asiatica) |
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Improves circulatory problems in the extremities and speeds healing. A rejuvenating herb that helps in wound healing, ulcerative conditions, depression and other nervous disorders. Improves muscle tone. and improves cardio-pulmonary function. normalizes blood pH. Supports liver and adrenal function. Known in Sanskrit as brahmi, meaning "bringing knowledge," and used to instill a sense of well being prior to meditation. This historical usage may be attributed to its effects on boosting acetylcholine. A potent antioxidant, it can raise levels of glutathione and antioxidant enzymes including catalase, glutathione peroxidase and superoxide dismutase.22,23. |
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Gymnema Sylvestre Leaf |
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(Gurmar) |
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Lowers blood sugar levels and helps to curb cravings for sweets by diminishing the taste bud to brain "sweet taste" response to sugar and supportive for normalizing blood sugar. Used in India as a daily garnish with meals. It also has been shown to increase fecal excretion of steroids and bile and inhibits mast cell release of histamine and hyaluronidase in allergic reactions.24,25,26,27 |
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Milk Thistle Seed |
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(Silibum marinum) |
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Protests the liver against toxins, particularly lipid peroxidation. Herbal antioxidant/free radical quencher. Leukotriene inhibitor. Regenerates liver cells and stimulates bile flow. Relaxes spasms. Sulfur source. Assists in regeneration of glutathione and restoration of cellular thiol status. Kidney support. Adrenal support. Aids inflammatory bowel disorders, weakened immune function. Helps to detoxify alcohol, drugs, and other chemical toxins.28,29,30. |
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Chinese Sarsaparilla |
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(Smilax Glabra) |
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A cooling, alterative herb that has antibiotic, anti-inflammatory, diuretic Used to clear toxins, particularly mercury and other heavy metals, and for liver, joint, skin, and urinary tract support, and skin. Enhances activities of antioxidant enzymes catalase, superoxide dismutase, and glutathione peroxidase.29,30. |
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Schisandra Fruit |
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(Schisandra chinensis) |
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Regulates secretion of body fluids, moistens dry and irritated tissues. Acts as a tonic for the nervous, urinary, and cardiac systems. Liver protectant. Used traditionally for asthma, night sweats, urinary disorders, chronic and early morning diarrhea, palpitations, insomnia, poor memory. Supports detoxification via recycling of glutathione. |
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Beet-derived hypoallergenic ascorbic acid |
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(Vitamin C) |
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Vitamin C facilitates enhanced synthesis and recycling of glutathione more effectively than either oral glutathione or N-Acetyl Cysteine.4,5,6,7 |
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L-Glycine |
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This amino acid is 1/3 of the tripeptide construct of glutathione, along with cysteine and glutamine. Glycine also functions as a the driving force for the singular glycine-driven phase II chemical detoxification pathway. This pathway clears phenols, salicylates, benzoates, excess organic acids, and many other toxins from the body. It is utilized in the construction of DNA and RNA, the synthesis of bile acids, in the repairing of damaged tissues, and is crucial in nervous system function as an inhibitory neurotransmitter.31,32, 33,34. |
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Natural Lemon flavor |
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(Citrus limon) |
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Improves digestion, lowers blood pressure, diuretic, reduces inflammation, promotes gluconoride detoxifcation, improves peripheral circulation, and controls bacterial and fungal infections. Used for indigestion, flatulence, diarrhea, infant colic, and shock. |
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Coconut glycerine |
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Inhibits cellular adhesion of bacteria and fungi, contains broad trace mineral profile. Provides sweetening and gentle laxative properties. |
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Herbathione is a proprietary formulary of herbs in a base of glycerine, distilled water and natural lemon flavor. This tincture is free of alcohol, gluten, casein, soy, corn, sugar, artificial colors, flavors, sweeteners, or preservatives. Shake well before each use and refrigerate after opening, |
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Herbathione Dosage: 2 full droppers under the tongue, 2-3 times a day 30 minutes before meals. Use 1 dropper 2x per day for children under five. Do not use with a cold/flu or during pregnancy or breast feeding, prior to surgical procedures, or concurrently with blood-thinning medications. Consult with a qualified health practitioner prior to use if you have pre-existing health conditions. |
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Citation References: |
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1.Patrick L.. Mercury toxicity and antioxidants: Part 1: role of glutathione and alpha lipoic acid In the treatment of mercury toxicity. Alternative Medical Review. 2002 Dec;7(6):456-71. |
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2. Sandir, R, Gill KD. Effect of lead on lipid peroxidation in liver of rats. Biological Trace Element Research. 1995 Apr;48(1):91-7. |
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3.Witschi A. The systemic availablilty of oral glutathione. European Journal of Clinical Pharmacology 1992 43 667-69 |
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4. Meister A. On the antioxidant effects of ascorbic acid and glutathione. Biochemical Pharmacology. 1992; 44:1905-15. |
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5Johnston CJ, Meyer CG, Srikakshimi JC. Vitamin C elevates red blood cell glutathione in healthy adults. American Journal of Clinical Nutrition. 58 103-5 1993 |
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6.Jain A, et al.,, Effect of ascorbate or N-acetylcysteine treatment in a patient with hereditary glutathione synthesase deficiency. Jouranl of Pediatrics 124 229-33 1994. |
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7.Das KK, Das Sn, DasGupta S. The influence of ascorbic acid on nickel-induced hepatic lipid peroxidation In rats. Journal of Basic Clinical Physiollogy and Pharmacology 2001;12(3):187-95 |
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8.Jain S, Shukla SD, Sharma K, Bhatnagar . Neuroprotective effects of Withania Somnifera Dunn. In hippocampal sub-regions of female albino rat. Phytotherapy Research 2001 Sep;15(6):544-8. |
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9.Davis L, Kuttan G, Immunomodulatory activity of Withania Somnifera. Journal of Ethnopharmacology 2000 Jul;71(1-2):193-200. |
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10.Bhattacharya SK, Satyan KS, Ghosal S. Antioxidant activity of glycowithanolides from Withania Somnifera. Indian Journal of Experimental Biology 1997 Mar;35(3)236-9. |
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11.Chaurasia SS, Panda S, Kar A. Withania Somnifera root extract in the regulation of lead-induced oxidative damage in the male mouse. Pharmacological Research 2000 Jun;41(6):663-6. |
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12.Lin SC, Chung TC, Linn CC, Ueng TH, Lin YH, Lin SY, Wang LY. Hepatoprotective effects of Arcticum Lappa on Carbon Tetrachloride and acetominophen-induced liver damage. Am Journal of Chinese Medicine 2000;28(2):163-73. |
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13. .Lin SC, Lin CH, Lin CC, Lin YH, Chen CF, Chen JC, Wang, LY. Hepatoprotective effects of Arcticum Lappa on liver injuries induced by chronic ethanol consumption & potentiated by carbon tetrachloride. Journal of Biomedical Science. 2002 Sep-Oct;9 (5):401-9. |
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14.Zhao KS; Mancini C; Doria G. Enhancement of the immune response in mice be Astragalus Membranaceus extracts. Immunopharmacology 1990 Nov-Dec;20(3):225- 33. |
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15.Zhang, ZL; Wen QZ; Liu CX. Hepatoprotective effects of Astragalus root. Journal of Ethnopharmacology 1990 Sep;30(2):145-9. |
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16.Toda S, Yase Y,Shirataki Y, Inhibitory effects of of Astragali Radix on lipid peroxidation and protein oxidative modification of mouse brain homogenate by copper. Phytotherapy Research 2000 Jun;(4):294-6. |
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17.Alexandrovich I, Rakovitskaya O, Kolmo E, Sidorova T, Shushunov I. The effect of fennel (Foeniculum Vulgare) seed oil emulsion In Infantile colic: a randomized, placebo- controlled study. Alternative Therapies In Health and Medicine 2003 Jul-Aug;(4):58-61. |
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18.Toda S. Inhibitory effects of aromatic herbs on lipid peroxidation and protein modification by copper Phytotherapy Research May;17(5)546-8. |
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19.Ozbeck H, Ugras S Dulger H, Bayram I, Tuncer I, Ozturk G, Ozturk. Hepatoprotective effect of Foeniculum vulgare essential oil. Fitoterapia 2003 Apr;74(3)317-9. |
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20Rimbach G, Gohil K, Matsugo S, Moini H, Saliou C, Virgili F, Weber SU, Packer L. Induction of glutathone synthesis In human keratinocytes by Gingko Biloba extract. Biofactors. 2001;15(1):39-52. |
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21Sasaki K, Hatta S, Wada K, Ueda N, Yoshimura T, Endo T, Sakata M, Tanaka T, Haga M. Effects of extract of Gingko Biloba leaves and Its constituents on carcinogen- metabolizing enzyme activites and glutathione levels In mouse liver. Life Science. 2002 Feb 22;70(14):1657-67 |
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22. Shukla A, Rasik AM, Dhawan BN. Asiaticoside-Induced elevation of antioxidant levels in healing wounds.Phytotherapy Research 1999 Feb;13(1):50-4. |
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23.Jayashee G, Kurup, Muraleedhara G, Sudarslal S, Jacob VB. Anti-oxidant activity of Centella Asiatica on lymphoma-bearing mice. Fitoterapia 2003 Jul;74(5):431-4. |
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24Harada S, Kasahara Y. Inhibitory effect of gurmarin on palatal taste responses to amino acids in the rat. Department of Oral 25Physiology, Kagoshima University Dental School, 8-35-1 |
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25Sugihara Y, Nojima H, Matsuda H, Murakami T, Yoshikawa M, Kimura I. Antihyperglycemic effects of gymnemic acid IV, a compound derived from Gymnema Sylvestre leaves in streptozotocin-diabetic mice. Journal of Asian Natural Product Research. 2000;2(4):321-7. |
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26Nakamura Y,Tsumura Y, Tonogi Y, ShibataT. Fecal steroid excretion is increased in rats by oral administration of gymnemic acids contained in Gymnema Sylvestre leaves. |
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27Sawabe Y, Nakagomi K, Iwagami S, Suzuki S, Nakawaza H. Inhibitory efects of pectic substances on activated hyaluronidase and histamine release from mast cells. Biochemical Biophys Acta. 1992 Nov 17;1137(3):274-8. |
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28.Valenzuela A, Aspillaga M, Vial S, Guerra, Selectivity of silymarin on the increase of the glutathione content in different tissues of the rat. Planta Medica 1989 Oct;55(5):420- 2. |
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29.Muriel P, Garciapina T, Perez-Alvarez V, Mourelle M. Silymarin protects against paracetomol-induced (acetominophen) lipid peroxidation and liver damage. Journal of Applied Toxicology. 1992 Dec;12(6):439-42. |
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30.Tager M, Dietzmann J, Thiel U, Hinrich, Neumann K, Ansorge S. Restoration of the cellular thiol status of peritoneal macrophages from CAPD patients by the flavinoids silibinin and silymarin. Free Radical Research. 2001 Feb;34(2):137-51. |
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29.Lee S, Ju E, Kim J. Free radical scavenging and antioxidant enzyme fortifying activities of extracts from Smilax China root. Experimental and Molecular Medicine. 2001 Dec;33(4):263-8. |
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30.Tripathi YB, Upadhyay AK, Chaturvedi P. Antioxidant property of Smilex China Linn. Indian Journal of Experimental Biology. 2001 Nov;39(11):1176-9. |
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Levy G. Pharmacokinetics of salicylate elimination in man. Journal of Pharmaceutical Science 1965; 232(3):864-72. |
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31.Patel DK, Ogunbuna A, Notarini, Bennet PN. Depletion of plasma glycine and effect of glycine by mouth on salicylate metabolism during aspirin 32..Timbrell JA Principles of biochemical toxicology. 2nd ed. London: Taylor and Francis, 1991 |
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33.Mulder GJ, editor. Conjugation reactions in drug metabolism: an integrated approach. London: Taylor and Francis, 1990. |
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overdose. Human Expermental Toxicology 1990;9:389-95. |
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34.Kimback G, Inal M, Baycu C. Ethanol-induced hepatotoxicity and protective effect of betaine (Trimethylglycine). Cellular Biochemical Function 2001 Dec;19(4):281-5. |
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Herbathione Product Page |
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The statements above have not been reviewed by the Food & Drug Administration. Neither these statements or the products referred to claim to treat, cure, or diagnose any disease or condition and are not intended to serve as a replacement for the services of a physician or other qualified healthcare practitioner. |